Purvalanol B(NG 95)
(2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL
CAS: 212844-54-7
Molecular Formula: C20H25ClN6O3
Purvalanol B(NG 95) - Names and Identifiers
Purvalanol B(NG 95) - Physico-chemical Properties
| Molecular Formula | C20H25ClN6O3 |
| Molar Mass | 432.9 |
| Density | 1.43±0.1 g/cm3(Predicted) |
| Melting Point | 58.5 °C |
| Boling Point | 660.6±65.0 °C(Predicted) |
| Solubility | DMSO: 37mg/mL, soluble |
| Appearance | solid |
| pKa | 2.81±0.25(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
Purvalanol B(NG 95) - Risk and Safety
| WGK Germany | 3 |
Purvalanol B(NG 95) - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.31 ml | 11.55 ml | 23.1 ml |
| 5 mM | 0.462 ml | 2.31 ml | 4.62 ml |
| 10 mM | 0.231 ml | 1.155 ml | 2.31 ml |
| 5 mM | 0.046 ml | 0.231 ml | 0.462 ml |
Last Update：2024-01-02 23:10:35
Purvalanol B(NG 95) - Reference Information
| biological activity | Purvalanol B (NG-95) is an effective and selective inhibitor of cyclin-dependent kinase (CDK), and its IC50 values for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35 are 6 nM, 6 nM, 9 nM and 6 nM respectively. |
| target | TargetValue cdc2-cyclin B (Cell-Free Assay) 6 nM CDK2-Cyclin A (Cell-Free Assay) 6 nM CDK5-P35 (Cell-Free Assay) 6 nM CDK2-Cyclin E (Cell-Free Assay) 9 nM |
| Target | Value |
| cdc2-cyclin B (Cell-free assay) | 6 nM |
| CDK2-Cyclin A (Cell-free assay) | 6 nM |
| CDK5-P35 (Cell-free assay) | 6 nM |
| CDK2-Cyclin E (Cell-free assay) | 9 nM |
Last Update：2024-04-10 22:29:15
Supplier List
Spot supply
Product Name: NG 95 Visit Supplier Webpage Request for quotationCAS: 212844-54-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Purvalanol B Visit Supplier Webpage Request for quotationCAS: 212844-54-7
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Spot supply
Product Name: Purvalanol B Visit Supplier Webpage Request for quotationCAS: 212844-54-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Purvalanol B Visit Supplier Webpage Request for quotationCAS: 212844-54-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: (2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL Visit Supplier Webpage Request for quotation
CAS: 212844-54-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 212844-54-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: NG 95 Visit Supplier Webpage Request for quotationCAS: 212844-54-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Purvalanol B Visit Supplier Webpage Request for quotationCAS: 212844-54-7
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Spot supply
Product Name: Purvalanol B Visit Supplier Webpage Request for quotationCAS: 212844-54-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Purvalanol B Visit Supplier Webpage Request for quotationCAS: 212844-54-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: (2R)-2-[[6-[(3-CHLORO-4-CARBOXYPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL Visit Supplier Webpage Request for quotation
CAS: 212844-54-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 212844-54-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
Purvalanol B(NG 95)
5-(1-[(4-BROMOPHENYL)SULFONYL]-2-PYRROLIDINYL)-4-METHYL-4H-1,2,4-TRIAZOL-3-YL 4-(TERT-BUTYL)BENZYL SULFIDE
4(5)-HYDROXYMETHYLIMIDAZOLE HYDROCHLORIDE
5-[[4-[2-[(5-Hydroxy-2-pyridinyl)MethylaMino]ethoxy-d4]phenylMethyl]-2,4-thiazolidinedione
4-AMINO-3-HYDROXY-6-IODO-1H-INDAZOLE
5-Chloro-4-Fluoro-2-Nitroacetanilide
PI-540
Talabostat Impurity 7
polypropylene
5-[[2-chloro-4-(methylsulphonyl)phenyl]azo]-4-methyl-2,6-bis[[3-(2-phenoxyethoxy)propyl]amino]nicotinonitrile
5-(1-[(4-BROMOPHENYL)SULFONYL]-2-PYRROLIDINYL)-4-METHYL-4H-1,2,4-TRIAZOL-3-YL 4-(TERT-BUTYL)BENZYL SULFIDE
4(5)-HYDROXYMETHYLIMIDAZOLE HYDROCHLORIDE
5-[[4-[2-[(5-Hydroxy-2-pyridinyl)MethylaMino]ethoxy-d4]phenylMethyl]-2,4-thiazolidinedione
4-AMINO-3-HYDROXY-6-IODO-1H-INDAZOLE
5-Chloro-4-Fluoro-2-Nitroacetanilide
PI-540
Talabostat Impurity 7
polypropylene
5-[[2-chloro-4-(methylsulphonyl)phenyl]azo]-4-methyl-2,6-bis[[3-(2-phenoxyethoxy)propyl]amino]nicotinonitrile